Description
- Mechanism of Action: SLU-PP-332 activates all three estrogen-related receptors (ERRα, ERRβ, and ERRγ), particularly ERRα, which regulates metabolic pathways usually turned on by exercise. This activation increases mitochondrial function and cellular respiration in energy-intensive tissues like muscle, heart, and brain
- “Exercise Mimetic” Effects: In mouse studies, the compound has been shown to induce physiological adaptations similar to aerobic exercise, including improved exercise endurance, increased oxidative muscle fibers, decreased fat mass, and enhanced glucose metabolism.
- Potential Therapeutic Use (Preclinical): Research suggests potential applications in treating metabolic diseases such as obesity, type 2 diabetes, non-alcoholic fatty liver disease, heart failure, and age-related muscle loss.
- Chemical Nature: Despite being frequently discussed in the “peptide” community, SLU-PP-332 is a small, non-peptide molecule with the chemical formula.




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